Dr Dean Wright
The previous two posts (one and two) sought to identify how the Set of the person influences the psychedelic experience. The current study seeks to understand how the ‘drug‘ affects the psychedelic experience.
The authors use the bounty of knowledge available from Erowid. They seek to help establish how different psychedelics influence the subjective effects of the experience.
They compare a variety of tryptamine and phenethylamine psychedelics on their chemical structure and ‘binding affinity‘ with various receptors. Binding affinities refer to how well a drug binds to and activates a receptor. They then map these binding affinities with the subjective effects reported by user reports on Erowid.